This site needs JavaScript to work properly. Graham S.P., McLean R.K., Spencer A.J., Belij-Rammerstorfer S., Wright D., Ulaszewska M., et al. He said the study shows how the. In this interview, we speak to Svea Cheeseman at Refeyn about their SamuxMP products used for the analysis of adeno-associated viruses (AAV) capsids. technical support for your product directly (links go to external sites): Thank you for your interest in spreading the word about The BMJ. Spike protein does not attack anything, it only aims to activate the immune response, it is not the same as coronavirus spike protein and after vaccination, it is created in a dose 100 thousand times lower than in viral infection. -, Schalk J.A.C., Mooi F.R., Berbers G.A.M., van Aerts L.A., Ovelgnne H., Kimman T.G. Biodistribution of AZD1222 following a single intramuscular injection in (a) male and (b) female mice. No report of Encephalitis japanese b is found for people with Helicobacter pylori associated gastrointestinal disease. Asano M, Okada H, Itoh Y, Hirata H, Ishikawa K, Yoshida E, Matsui A, Kelly EJ, Shoemaker K, Olsson U, Vekemans J. Int J Infect Dis. Listing a study does not mean it has been evaluated by the U.S. Federal Government. 2020;5(1) doi: 10.1038/s41541-020-00221-3. You can view The Poynter Institutes most-recent public financial disclosure form 990. So just what benefit is there in seeking, and granting, a BLA? Among the six first in disease vaccines approved by the FDA since 2006, pre-licensure pivotal trials were a median of 23 months in duration, according to a recent analysis.9, Six months also seems substantially shorter than previously conceptualised expectations. That claim has been resurrected for COVID-19 vaccines. 2021 Jun 17;9 (6):662. doi: 10.3390/vaccines9060662. He is also engaged by Elders Without Borders as an expert witness on behalf of Adam Skelly (owner of Adamson BBQ), and has testified against the effectiveness of masks, against lockdowns, and against the experimental vaccines (which he reasons are unnecessary with his proposed treatment ivermectin). AZD1222 (ChAdox1 nCov-19) is a replication-deficient non-human adenovirus-vectored vaccine for coronavirus disease 2019. The recent reports of cerebral venous sinus thrombosis (CVST) following administration of CoViD-19 viral vector vaccines (AZ/Oxford and J&J/Janssen) have a peculiar clinical presentation exhibiting haemorrhage, blood clots and thrombocytopenia. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. US Food and Drug Administration. Two more vaccines were also approved in May 2021 using the Tokurei system. (part2) and Phase 3 additional dose clinical trial in Japanese pediat ric subjects of its vaccine (code No. US Food and Drug Administration. As you might guess, he is an antivaxxer, antimasker, and COVID-19 conspiracy theorists and has made a number of false claims about vaccines dating back to the early days of the pandemic. Thomas, Liji. But it was the focus of much discussion back in September 2020. 161st Vaccines and Related Biological Products Advisory Committee (VRBPAC) meeting. The mitigating factors include the non-serious and self-limited nature of the VAE for the most part, coupled with 94% protection against symptomatic confirmed COVID-19 after two doses of the Moderna mRNA vaccine. Liji practiced as a full-time consultant in obstetrics/gynecology in a private hospital for a few years following her graduation. She wrote a book about it, Undercover Epicenter Nurse: How Fraud, Negligence, and Greed Led to Unnecessary Deaths at Elmhurst Hospital. https://www.ema.europa.eu/en/documents/assessment-report/covid-19-vaccin https://assets.publishing.service.gov.uk/government/uploads/system/uploa Womens, childrens & adolescents health. But those fears largely dissipated when the FDA published a guidance document in early October outlining its expectations for the EUA. Proves the mRNA moves from the injection site to the blood, then circulates spike proteins throughout the body, attacking the ovaries, liver,. Have a history of immunodeficiency or having a close relative with congenital immunodeficiency. Disclaimer, National Library of Medicine New study out of Harvard and published by Circulation: Free Spike Protein - Not Bound by Antibodies - Detected in the Blood of Adolescents and Young Adults Who Brian Van Hecke LinkedIn: Circulating Spike Protein Detected in Post-COVID-19 mRNA Vaccine Myalgia and tiredness were very common, compared to headaches in other reports. ), As hundreds of millions of people around the world get vaccinated, it may seem like wordsmithing to highlight the fact that none of the covid-19 vaccines in use are actually approved. Through an emergency access mechanism known as Emergency Use Authorisation (EUA), the products being rolled out still technically remain investigational.3 Factsheets distributed to vaccinees are clear: There is no FDA approved vaccine to prevent covid-19.4, The approval-authorisation distinction is often misunderstood by the media,5 even in the scientific press. Epub 2021 Oct 22. van Doremalen N, Purushotham JN, Schulz JE, Holbrook MG, Bushmaker T, Carmody A, Port JR, Yinda CK, Okumura A, Saturday G, Amanat F, Krammer F, Hanley PW, Smith BJ, Lovaglio J, Anzick SL, Barbian K, Martens C, Gilbert SC, Lambe T, Munster VJ. 1 min read. sharing sensitive information, make sure youre on a federal (Or maybe they were combining the vaccines are sterilizing our women trope with the toxins gambit. The USs Operation Warp Speed delivered on its promise to get a novel vaccine into arms in record time (box). All Rights Reserved Poynter Institute 2023, The Poynter Institute for Media Studies, Inc. is a non-profit 501(c)3. The study 514559 was aimed to examine the biodistribution of ChAdOx1 nCoV-19 in bone marrow, brain, spinal cord, sciatic nerve, and other body tissues. LLOQ, lower limit of quantification. More tellingly, though, antivaxxers are portraying the Japanese biodistribution study as though it were some sort of secret document. [8] Contents 1 Background 1.1 Vaccines on order For general information, Learn About Clinical Studies. (That longtime antivaccine activist J.B. Handley, who has more recentlyand not unexpectedlyjoined the COVID-19 conspiracy theory antimask grift train, wrote the foreword should tell you all you need to know about this book, as should the endorsement by Joe Mercola.) Clipboard, Search History, and several other advanced features are temporarily unavailable. RT @cov19treatments: Dr. Byrum Bridle, ON Point with Alex Pierson New peer reviewed study on COVID-19 products biodistribution study from Japan mRNA goes to the ovaries, adrenals, suggests why heart inflammation, blood clots and other dangerous side effects occur. Choosing to participate in a study is an important personal decision. Blood clearance rates of adenovirus type 5 in mice. The researchers point out that available data on Japanese people who got two doses of the Comirnaty vaccine were more likely to develop VAE after the second dose. According to the Guidance for Medical Practice for COVID-19 (Ver 4.1), Japan has two recommended treatments for COVID-19: remdesivir (RNA synthetic enzyme inhibitor) and dexamethasone (steroidal anti-inflammatory drug, SAD). Why? Bethesda, MD 20894, Web Policies Aiming to improve scientific literacy in this age of information overload and mis/disinformation, especially on controversial and polarizing topics. PMC Results show that AZD1222 was safe and well tolerated, with a spread that was largely confined to administration sites and the proximal sciatic nerve, with low levels observed in sites that are involved in rapid clearance of particulates by the reticuloendothelial system. Now that Ive established the origin of the antivaccine misuse of the biodistribution study, at least as closely as I can, lets take a look at the claims of Ms. Olszewski, Mr. Adams, and Dr. Bridle themselves and compare them to the actual study, so helpfully stored at so many antivaccine websites. In early October 2021, data from the government shows that 60.9% of people have had their second dose, while 71.3% have received first shot. National Center for Complementary and Integrative Health, Steven P. Novella, MD Founder and Executive Editor, David H. Gorski, MD, PhD Managing Editor. . Secret!) But whats the rush, asks Peter Doshi, and is just six months of data from now unblinded trials acceptable? Pfizer. 2006;2(2):4553. A health worker prepares a dose of the Pfizer-BioNTech vaccine against COVID-19 at a vaccination center in Santiago, on January 20, 2022. Perhaps Bridles most famous quote was cited by Adams: In short, the conclusion is we made a big mistake. Vz/F of plasma MAFB-7566a and constituent lipids of LNP will be assessed. For instance, behold Alex Berenson, the " pandemic's wrongest man ", crowing about the study: The younger generation's hesitancy towards the COVID-19 vaccine in Japan received significant attention during the early stages of vaccination. You can view The Poynter Institutes most-recent public financial disclosure form 990. Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper: [All authors are employed by AstraZeneca]. mRNA Medicine: whats next after the COVID-19 vaccine? The human vaccine contains 0.43 mg ALC-0315=(4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate), ALC-0159=0.05 mg 2[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide, 0.09 mg 1,2-distearoyl-sn-glycero-3- phosphocholine, and 0.2 mg cholesterol. Sound familiar? 2021 Aug 18;13(607):eabh0755. Healthy elderly participants will be randomized to receive a intramuscular injection of placebo. (The situation is similar in Europe, where four covid-19 vaccines have been granted conditional marketing authorisations, a fast track mechanism that can be used in emergencies. Have a history of anaphylaxis or severe allergies due to food, cosmetics, medicines, or vaccination. -, Alemany R., Suzuki K., Curiel D.T. given the properties of coronavirus variants. This false claim originated from: viral social media post. 2022 Jun 11;399(10342):2212-2225. doi: 10.1016/S0140-6736(22)00770-X. David H. Gorski, MD, PhD, FACS is a surgical oncologist at the Barbara Ann Karmanos Cancer Institute specializing in breast cancer surgery, where he also serves as the American College of Surgeons Committee on Cancer Liaison Physician as well as an Associate Professor of Surgery and member of the faculty of the Graduate Program in Cancer Biology at Wayne State University. Biodistribution of AZD1222 following a single intramuscular injection in (a) male and (b), MeSH She has counseled hundreds of patients facing issues from pregnancy-related problems and infertility, and has been in charge of over 2,000 deliveries, striving always to achieve a normal delivery rather than operative. Current trials arent designed to tell us, An overview of vaccine development, approval, and regulation, with implications for covid-19, World Health Organization Solidarity Vaccines Trial Expert Group. 2020. Link Between Pfizer-BioNTech COVID-19 Vaccine and Stroke We simply knew that there is no truly new trope, pseudoscience, or disinformation in the antivaccine narratives and conspiracy theories; so all we did was to predict the repurposing of tried-and-not-true antivax lies. In the past few months, there has been a push for the idea that the spike proteins related to mRNA vaccines are toxic to our bodies. LA JOLLAScientists have known for a while that SARS-CoV-2's distinctive "spike" proteins help the virus infect its host by latching on to healthy cells. and transmitted securely. Careers. Please use one of the following formats to cite this article in your essay, paper or report: Thomas, Liji. This time, its the lipid nanoparticles attacking the ovaries, echoing very old claims about polysorbate-80. As noted in my last article on BioNTech's "brazen" avoidance of safety testing of its Covid-19 vaccine, BioNTech founders Ugur Sahin and zlem Treci claim in their book The Vaccine that the company's Covid-19 vaccine project got underway on January 27, 2020. The pharmacovigilance data confirmed the CVST incidences with all genetic vaccines (viral or non-viral vector), however, the regulatory authorities in their recent investigations reported that the CVST was unusually accompanied with thrombocytopenia in subjects injected with CoViD-19 viral vector vaccines (such as AstraZeneca and J&J/Janssen) than those injected with mRNA vaccines. At peak, only 0.02% made it to the brain. Even if you used much older rats, who can weigh as much as twice as much, that would still translate to a dose of 125 g/kg. Moderna did not respond and Janssen only confirmed it intended to apply for a BLA later in 2021. Pfizer likewise did not answer but instead quoted an FDA webpage on medical devices, which stated: Sponsors of EUA products are encouraged to follow up the EUA with a pre-market submission so that it can remain on the market once the EUA is no longer in effect.16 But EUAs have no built-in expiry datein fact, 14 EUAs for Zika diagnostic tests remain active despite the public health emergency expiring in 2017.17, Cody Meissner told The BMJ he saw some distinct advantages of a BLA over EUA. As pointed out by multiple sources, the peak accumulation in the ovaries was 0.095% (or less than 1:1,000 of the total dose of lipid nanoparticle): One wonders, one does, why antivaxxers arent going ballistic about this finding. The second source Bridle cited during his interview is a "biodistribution study" obtained from the Japanese Pharmaceuticals and Medical Devices Agency. The BMJ asked Moderna, Pfizer, and Janssen (Johnson and Johnson) what proportion of trial participants were now formally unblinded, and how many originally allocated to placebo have now received a vaccine. On the contrary, modern genetic vaccines work on the premise of gene delivery, therefore, a detailed biodistribution and pharmacokinetic evaluation of the formulated product is invaluable in understanding the potential impact of vaccine encoding gene transfection to various body tissues beyond the site of injection. Tmax of plasma MAFB-7566a and constituent lipids of LNP will be assessed. Authors Ryo Okubo 1 , Takashi Yoshioka 2 , Satoko Ohfuji 3 , Takahiro Matsuo 4 , Takahiro Tabuchi 5 Affiliations This is also likely with the Moderna vaccine. Please note that medical information found
Key questions about covid-19 vaccine mandates. Developed in record time, the Pfizer and Moderna vaccines, built on a messenger ribonucleic acid (mRNA) platform that encodes the viral spike antigen, were the first to receive emergency use authorization. Indeed, a year ago Dr. Bridle received a $230,000 grant from the provincial government to develop a vaccine using the very same spike protein that hes been demonizing, although that might be the big mistake he has been confessing to. 2020. doi: 10.1126/scitranslmed.abh0755. Kaplan K. The FDA didnt approve Pfizers covid-19 vaccine. Meissner responded that a BLA would not be issued until the FDA is convinced of the short and long term safety of these vaccines. In this nonclinical study, the biodistribution of AZD1222 was assessed in mice for 29 days following intramuscular injection. The biodistribution of ChAdOx1 encoding nCoV-19 following intramuscular injection in mice (study 514559) was ongoing at the time of its regulatory approval [4]. Remember to check the date when the fact-check you are reading was published before sharing it. Due to the immense economic fallout of these measures, vaccination has long been held to be the only way out of this situation. The most common was pain, in 70%, followed by swelling and local heat in about 35-40%. Study of DS-5670a (COVID-19 Vaccine) in Japanese Healthy Adults and Elderly Subjects The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Pfizer and BioNTech confirm high efficacy and no serious safety concerns through up to six months following second dose in updated topline analysis of landmark COVID-19 vaccine study. As Yuri Deigin pointed out, only around 0.1% of the dose of lipid nanoparticles went to the ovaries. [18F]GTP1 in Healthy Japanese Subjects: Actual Study Start Date : August 11, 2020: Actual Primary Completion Date : October 9, 2020: Actual Study . Before that, he had been spreading misinformation about the deadly spike protein produced by COVID-19 vaccines: Dr Byram Bridle, Professor of Viral Immunolog: The spike protein in the covid vaccines is a very dangerous toxin. Lee SW, Moon JY, Lee SK, Lee H, Moon S, Chung SJ, Yeo Y, Park TS, Park DW, Kim TH, Sohn JW, Yoon HJ, Kim SH. You can never get unvaccinated. MISSING CONTEXT: A Japanese study on the bio-distribution of Covid-19 products shows that mRNA travels to the ovaries and adrenal glands, suggesting why heartburn, blood clots, and other. This site complies with the HONcode standard for trustworthy health information: verify here. 2022 Apr 12;13:836492. doi: 10.3389/fimmu.2022.836492. Some examples of these vaccines include AstraZeneca/Oxford (Chimp adenoviral vector), J&J/Janssen (Human adenoviral vector 26), CanSinoBio (Human adenoviral vector 5), and Sputnik V (Human adenoviral vectors 26 and 5). And less that 0.1% of the dose went there! In short, this study has found a spike glycoprotein body-wide biodistribution which was followed by a slow regional elimination in 2-3 months old male mice, except for the liver, which actually. They were 56% more likely to develop induration and itching at the site of injection. All adverse events occurring within 30 minutes of administration of the vaccine were described. Explanation: We deem this post as disinformation when it is claimed that the spike protein attacks the ovaries, the neurological system, and other organs. COVID-19 Vaccine Moderna (COVID-19 mRNA Vaccine (nucleoside-modified)), EMA/15689/2021 Corr.1 2021. The long-term goal is to have a flexible technological platform to rapidly develop vaccines against highly pathogenic coronaviruses that may emerge in the future. Many developed countries have achieved vaccination of over half of their adult population, beginning with the elderly, more vulnerable subsets. European Medicines Agency. However, the detailed tissue-specific distribution of mRNA vaccines encoding SARS-CoV-2 spike proteins (Pfizer or Moderna) is not fully known that can offer invaluable insights into the potential safety of these vaccines in peoples with pre-existing conditions or those on certain medications. In fact, this new version of the vaccines are going to sterilize our womenfolk disinformation leads me to conclude that just as aluminum became the new mercury as the science became clear that mercury in the thimerosal preservative that used to be in some childhood vaccines does not cause autism, lipid nanoparticles are the new polysorbate-80. Dr. Liji Thomas is an OB-GYN, who graduated from the Government Medical College, University of Calicut, Kerala, in 2001. Minors (below 20 years of age) also had more local and systemic adverse events. For example, Geert Vanden Bossche, who is also spreading misinformation about COVID-19 vaccines, owns a company that is trying to develop a vaccine based on a technology to activate natural killer cells. Epub 2021 Jul 27. Janssen told The BMJ: We do not have specific figures on how many of our study participants have received a vaccine at this time. But the company confirmed it was implementing an amended protocol across all countries to unblind all participants in its two phase III trials, the earlier of which passed the median of two month follow-up mark in January. According to this study, there was no difference in ovarian function between those who were infected with the Covid-19 and those who were not. However, for the typical 70 kg male, 0.5 mg represents a per-weight dose of 0.0071 mg/kg, or 7.1 g/kg. Assessment Report. So, the more appropriate number to look at is the % of total vaccine administered, and the Japanese study noted that <1% of the vaccine ended up in the ovaries. Cody Meissner, a professor of paediatrics at Tufts University and member of the FDAs advisory committee, was curious. Adverse events following COVID-19 virus vaccination in Japanese young population: The first cross-sectional study conducted by a questionnaire survey after the first-time-injection, https://doi.org/10.1101/2021.07.23.21261029, https://www.medrxiv.org/content/10.1101/2021.07.23.21261029v1, Researchers study congenital abnormalities after COVID-19 infection and vaccination, Real-world effectiveness of the bivalent vaccine for preventing COVID-19 hospitalizations in non-hospitalized subjects, Profound immune escape by SARS-CoV-2 XBB.1 even after 4 vaccine doses, MIS-C more common and severe than previously thought, SARS-CoV-2 WA1/2020, Delta and Omicron strains found to infect human sensory neurons, Study shows booster vaccinations against SARS-CoV-2 effective but protection wanes rapidly, COVID-19 booster doses could significantly reduce the incidence of SARS-CoV-2 infection among young adults, Study explores incidence, severity, and long COVID associations of SARS-CoV-2 reinfections, Beverage fructose intake may lead to an abnormal cardiometabolic profile, Researchers explore multi-syndrome prediction of dementia syndromes, Breast milk of people vaccinated against COVID-19 provides protection to infants, study reveals, Association of aldosterone with ideal cardiovascular health in incident diabetes. Biodistribution studies of adenovirus-based vaccines support their clinical development by evaluating their spread and persistence following in vivo administration. Nania R. FDA commissioner Stephen Hahn on covid vaccine safety. And so it came to pass beginning as soon as the vaccines neared approval under an emergency use authorization (EUA) by the FDA that antivaxxers repurposed all their old tropes for COVID-19 vaccines, claiming that they were loaded with toxins (the lipid nanoparticles in the mRNA-based vaccines, given that they cant contain aluminum, dont you know? Are COVID-19 Hospitalizations for Children Inflated? A World Health Organization expert group on covid-19 vaccines (which included FDA regulators) in August 2020 called for follow-up until at least month 12, or until an effective vaccine is deployed locally.10 Another group, composed of industry and academic authors, similarly wrote in October 2020: we recommend longer term follow-up of all participants for at least a year after randomisation.11. The COVID-19 pandemic has caused major disruption to healthcare systems with significant socioeconomic impacts. Maybe its because saying that lipid nanoparticles cause female infertility is more scary than saying they take a while to be eliminated from the liver. Maybe its because, at the peak, the amount of lipid nanoparticles detected in the liver was only 18%. At the intersection of these two programs, is a research initiative aimed at modifying the research teams optimized cancer vaccine platforms to target severe acute respiratory syndrome coronavirus (SARS-CoV)-2, which is the causative agent of the coronavirus disease identified at the end of 2019 (COVID-19). Healthy adults participants will be randomized to receive a intramuscular injection of DS-5670a 100 g. 301 Japanese responded to an online survey in February 2021, in which they first . The vaccine can cause spike protein deposition in the. Such data is crucial in delineating the safety and efficacy of this intervention in various age groups. He has conflated spike protein with lipid nanoparticles, not just once, but repeatedly. Epitope mapping reveals the humoral responses against the main SARS-CoV-2 structural proteins in infected patients from Africa, Mercy Medical Center secures top rank from Healthgrades for surgical care in Maryland, Investigational vaccine regimen safe but did not provide protection against HIV acquisition, Researchers use single-cell RNA-sequencing to study the aging peripheral blood in mice, Accurate information about what most other people are doing can boost vaccine uptake. Moderna TX. The Male Contraceptive Pill: is it possible? One key difference between EUA and approval (also called licensure, and which for vaccines is known as a BLA (Biologics License Application)) was the expected length of follow-up of trial participants. Vaccines are one of the great discoveries in medicine that has improved life expectancy dramatically. https://www.news-medical.net/news/20210806/Study-reports-on-COVID-19-vaccine-related-adverse-events-in-young-Japanese-population.aspx. I will admit that there were a couple of new ones, albeit variations on a theme. It is updated regularly. (Clinical Trial), Triple (Participant, Care Provider, Investigator), A Phase 1/2 Study to Assess the Safety, Immunogenicity and Recommended Dose of DS-5670a (COVID-19 Vaccine) in Japanese Healthy Adults and Elderly Subjects, 20 Years to 74 Years (Adult, Older Adult). Bridle argues that unlike traditional vaccines that stay mostly in the vaccination site at the shoulder muscle, the Japanese study showed how the spike protein of the coronavirus enters the bloodstream and circulates around the body for several days after a person gets inoculated with the vaccine. They also address vaccine safety. The researchers explored the adverse events reported after the administration of the first dose of the Comirnaty and Moderna vaccines. But the FDAs official position on minimum follow-up before licensure is unclear at best. The vaccine may therefore spur the brain cells to produce CoViD spike proteins that may lead to an immune response against brain cells, or it may spark a spike protein-induced thrombosis. The surrogate studies with luciferase and solid-lipid nanoparticles (Pfizer) confirm a biodistribution to the liver and other body tissues beyond the administration site [5]. But approving a vaccine in order to legally support mandates or convince people of its safety arguably puts the cart before the horse. An approved vaccine, for one, would provide an element of assurance, increasing public trust in the vaccines, particularly for those currently sitting on the fence. The analysis included approximately 1,900 participants, two-thirds of them being women. with these terms and conditions. Listing a study does not mean it has been evaluated by the U.S. Federal Government. 2021. So I guess I should say that theres almost nothing new under the sun. Most local events occurred within a day of injection and resolved spontaneously, though redness and itching at the injection site persisted in over a quarter, and just under a fifth, of the subjects, respectively. Accordingly, levels of AZD1222 decreased from Day 2 to Day 29, indicating clearance. Copyright 2021 The Authors. Because lest we forget, all covid-19 vaccines currently in use in the US are available under emergency access only. With large phase III trials by Pfizer and Moderna well under way, and the November US presidential election looming, many worried about political pressure resulting in the rollout of an unsafe or ineffective vaccine.6. Because thats our best way of knowing.13. Fatigue was also reported to occur on the same day, lasting for up to three days afterward. Yet another study has shown that vaccination against COVID-19 has no effect on immunological tolerance of the fetus by the mother. Both lipids are eliminated rapidly from the plasma by several logs, such that by 300 hours (12.5 days) after injection very little is detectable. (2021). No long-term studies. Very often, its the fact that we have that placebo controlled follow-up over time, that gives us the ability to say that the vaccine didnt cause something at a longer period of time after vaccination, the FDAs Philip Krause explained last December.13. News-Medical. However, in the absence of the results of study 514559, the biodistribution of ChaAdOx1 HBV in mice (study 0841MV38.001) confirms the delivery of vaccine into the brain tissues. The EIN for the organization is 59-1630423. Talk with your doctor and family members or friends about deciding to join a study. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04821674. For example, with accumulating in the ovaries, one of my questions is, will we be rendering young people infertile, some of them infertile? So, Ill stop there. Healthy elderly participants will be randomized to receive a intramuscular injection of DS-5670a 60 g. Healthy adults participants will be randomized to receive a intramuscular injection of DS-5670a 10 g. About three weeks ago, antivaxxers started pointing to a study from the Salk Institute as yet more "proof" that the spike protein used in COVID-19 vaccines is toxic and deadly. FOIA For COVID-19 Vaccine Moderna, a biodistribution study using a qualified multiplex branched DNA . Lancet. eCollection 2022. Conspiracy theorists being conspiracy theorists, Nurse Erin says that the claim that lipid nanoparticles from the Pfizer vaccine adhere to the ovaries is based on a leaked confidential study from Pfizer (of course). Spike protein does not sufficiently resemble syncytin to cause miscarriages and infertility, and the lipid nanoparticles in the vaccines do not accumulate in the ovaries, much less cause female infertility. 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